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Signs and symptoms. Can itching be a sign of breast cancer Extramammary Paget's disease Heart failure is a pathophysiological state in which cardiac output is insufficient in meeting the needs of the body and lungs. Exposure to large doses of radiation, such as those given during radiation therapy for cancer, increases the risk of bone cancer in the future. Paget's Disease of Bone Mild or early cases of Paget's are asymptomatic, and so most people are diagnosed with Paget's disease incidentally during medical evaluation for another problem. Paget's disease of the breast: there is a role for breast-conserving therapy. Radiation therapy for cancer. Leg Pain: Symptoms, Signs Wikipedia Mayo Clinic Pagets disease is an uncommon condition, accounting for only 1 to 3 percent of all breast cancer cases. It usually first appears as a red, scaly rash of the skin that may look like eczema. The clinical presentation of this disease is similar to the characteristics of mammary Paget's disease (MPD). The term "congestive heart failure" is often used, as one of the common symptoms is congestion, or build-up of fluid in a person's tissues and veins in the lungs or other parts of the body. It can often control the disease for years. It can often control the disease for years. In Paget's disease, this process is abnormal. Many people with Paget's disease do not have any symptoms at all. When symptoms do occur, they may be Symptoms of Pagets Disease. Symptoms and signs of Pagets disease of the bone can include: Bone or joint pain: This could be caused by Pagets disease or by arthritis, which is a complication of Pages disease of the bone. Most commonly occurring in older adults, Paget's disease of bone can increase the risk of bone cancer developing later. Symptoms of Paget's disease of bone include bone pain, joint pain and problems caused by a nerve being squashed or damaged. Another theory is that the disease can develop independently in the nipple. Familial adenomatous polyposis This condition develops in the nipple or the darker area of skin around it (the areola). Home Page: American Journal of Obstetrics & Gynecology Paget's disease of the breast is a type of cancer that outwardly may have the appearance of eczema, with skin changes involving the nipple of the breast.The condition is an uncommon disease accounting for 1 to 4.3% of all breast cancers and was first described by Sir James Paget in 1874.. Disease Familial adenomatous polyposis (FAP) is an autosomal dominant inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine.While these polyps start out benign, malignant transformation into colon cancer occurs when they are left untreated. Tests and procedures used to diagnose Paget's disease of the breast include: Breast exam. Tests and procedures used to diagnose Paget's disease of the breast include: Breast exam. This condition develops in the nipple or the darker area of skin around it (the areola). Pinched nerves leading to tingling or numbness (if the disease affects the spine). Three variants are known to exist, FAP and attenuated FAP (originally called Paget's disease of bone Paget's Disease Anti-NMDA receptor encephalitis Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face, a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals poorly. The disease is often first discovered when X-rays are taken for another reason or when routine blood work indicates an elevated blood serum alkaline phosphatase level. Join LiveJournal Annals of Surgical Oncology 2005;12(5):391397. Numbness Causes Paget's disease of bone Paget's disease of bone is a chronic bone disorder. Paget's disease Numbness Causes Exposure to large doses of radiation, such as those given during radiation therapy for cancer, increases the risk of bone cancer in the future. The disease predominantly occurs in women over the age of 50. Symptoms. Password requirements: 6 to 30 characters long; ASCII characters only (characters found on a standard US keyboard); must contain at least 4 different symbols; Hearing loss and headaches (if the disease affects the skull). Original Research Gynecology Open Access. Enlarged bones. Show Sources SOURCES: Numbness commonly affects nerves outside of the brain and spinal cord, usually causing a lack of sensation in the arms, legs, hands and feet. Commonly affected areas include the pelvis, spine and skull. Numbness commonly affects nerves outside of the brain and spinal cord, usually causing a lack of sensation in the arms, legs, hands and feet. Hearing loss and headaches (if the disease affects the skull). 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